BRCA1 and BRCA2
Genes whose mutations significantly raise the risk of breast and ovarian cancers.
What it is
BRCA1 and BRCA2 are genes that help repair damage to our DNA. When these genes have mutations, they can't do their job properly, which can lead to an increased risk of breast and ovarian cancers. Think of it like a pair of molecular 'safety nets' that help prevent cancer-causing damage to our cells.
How it works
In normal cells, BRCA1 and BRCA2 genes help fix mistakes in our DNA that can lead to cancer. When these genes are mutated, the cell's ability to repair DNA damage is impaired, which can cause uncontrolled cell growth and tumor formation. This is why people with BRCA1 and BRCA2 mutations are at higher risk of developing breast and ovarian cancers.
Why it matters
Understanding BRCA1 and BRCA2 mutations is important for people who may be at risk of developing breast and ovarian cancers. Knowing about these mutations can help guide genetic testing and screening decisions, which can lead to earlier detection and treatment of cancer. This knowledge can also inform family planning and risk-reducing strategies for those with a family history of these cancers.
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional for guidance on your health.