← Cancer Research Glossary

Chimeric antigen receptor (CAR) T-cell therapy

A type of immunotherapy that genetically engineers a patient's own T cells to recognise and destroy cancer cells.

What it is

Chimeric antigen receptor (CAR) T-cell therapy is a type of treatment that uses a patient's own immune system to fight cancer. It involves taking T cells, a type of immune cell, from the patient's blood and genetically modifying them to recognize and target cancer cells. This modified T cell is then returned to the patient's body where it can help destroy cancer cells.

How it works

The process of CAR T-cell therapy typically begins with a blood test to collect T cells. These T cells are then sent to a laboratory where they are modified with a special receptor that allows them to recognize and bind to specific proteins on cancer cells. Once the modified T cells are returned to the patient's body, they can multiply and attack cancer cells. In some cases, this can lead to a significant reduction in cancer cells.

Why it matters

Understanding CAR T-cell therapy is important for patients and families affected by cancer, as it represents a new approach to treating certain types of cancer. While it may not be suitable for everyone, it can be a valuable option for those who have not responded to other treatments. Researchers are also studying CAR T-cell therapy to see if it can be used to treat other types of diseases.

This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional for guidance on your health.