← Cancer Research Glossary

KRAS mutation

One of the most common cancer-driving mutations, found in lung, colon, and pancreatic cancers.

What it is

A KRAS mutation is a change in the KRAS gene, which is a set of instructions inside our cells. This gene helps control how cells grow and divide. When the KRAS gene is mutated, it can cause cells to grow and divide too quickly, leading to cancer.

How it works

In some cases, a KRAS mutation can turn on a signal that tells cells to keep growing and dividing, even when they shouldn't. This can lead to the formation of a tumor. Researchers are still learning about how KRAS mutations work, but they think it may be related to the way cells respond to signals that tell them to grow or stop growing.

Why it matters

Understanding KRAS mutations is important because they are found in many types of cancer, including lung, colon, and pancreatic cancer. Knowing if a tumor has a KRAS mutation can help doctors decide which treatments may be most effective. Researchers are also studying KRAS mutations to learn more about how cancer develops and to find new ways to treat it.

This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional for guidance on your health.