← Cancer Research Glossary

Gene mutation

A change in DNA sequence that can drive cancer development.

What it is

A gene mutation is a change in the instructions that are stored in our DNA. DNA is like a set of instructions that tell our cells what to do and how to grow. When a gene mutation occurs, it can affect how these instructions are carried out, which may lead to problems with cell growth and division.

How it works

Gene mutations can happen in many different ways, such as when there's an error during DNA replication or when our environment exposes us to things that damage our DNA. In some cases, these mutations can be passed down from one generation to the next. When a gene mutation occurs in a cell, it can cause the cell to grow and divide in an uncontrolled way, which is a hallmark of cancer.

Why it matters

Understanding gene mutations is important for cancer research because it can help scientists identify the underlying causes of the disease. This knowledge can also inform the development of new treatments that target specific genetic changes. By studying gene mutations, researchers may be able to identify people who are at higher risk of developing certain types of cancer.

This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional for guidance on your health.