High-intensity focused ultrasound (HIFU)

What it is

High-intensity focused ultrasound (HIFU) is a non-invasive cancer treatment that uses sound waves to heat and destroy cancer cells. It is used for various types of cancer, including uterine fibroids, prostate cancer, and pancreatic cancer.

What research shows

Studies suggest that HIFU can effectively treat uterine fibroids, with some patients experiencing significant reduction in symptoms and tumor size. For prostate cancer, HIFU has been shown to be effective in treating localized tumors, with some studies reporting high rates of local control and minimal side effects. However, more research is needed to determine its long-term efficacy and optimal patient selection.

Current status

HIFU is a promising treatment option for certain types of cancer, particularly for patients who are not good candidates for surgery or radiation therapy. However, its limitations and optimal patient selection require further research.

Key studies

• PMID 41771218

  This study assessed functional and oncologic outcomes of prostate gland ablation using HIFU compared to standard treatments.

  PubMed ↗
• PMID 41766329

  This study aimed to develop and validate a nomogram for predicting HIFU ablation efficacy in uterine fibroids based on oxytocin-induced arterial-phase perfusion delay and ultrasound features.

  PubMed ↗
• PMID 41716957

  This study investigated the feasibility and outcomes of perirectal spacer implantation in previously treated prostate cancer patients undergoing salvage proton therapy radiation.

  PubMed ↗
• PMID 41678176

  This study compared salvage focal therapy with HIFU to salvage radical prostatectomy for localized radiorecurrent prostate cancer.

  PubMed ↗
• PMID 41643054

  This study investigated the feasibility and outcomes of salvage single-port transvesical robotic radical prostatectomy following HIFU therapy.

  PubMed ↗