Photodynamic therapy
Light-activated drug that selectively destroys cancer cells.
What it is
Photodynamic therapy (PDT) is a treatment that uses light to kill cancer cells. It works by using a light-sensitive medication that is activated by a specific wavelength of light, which then produces a form of oxygen that damages cancer cells.
What research shows
Studies suggest that PDT can be effective in treating various types of cancer, including skin, bladder, and gynecological tumors. Clinical trials have shown that PDT can lead to tumor response rates and improved local control, although more research is needed to fully understand its effects. Patient populations studied have included those with skin cancer, bladder cancer, and gynecological tumors.
Current status
PDT is a treatment option that is being explored for various types of cancer, but its use is still limited and more research is needed to fully understand its effects and optimal applications. Further studies are required to determine its efficacy and safety in different patient populations.
Moderate evidenceKey studies
- PMID 41836720PubMed ↗
Researchers developed a novel nanomaterial, Cu-Cy Nps@ZIF-8@HA, for photodynamic therapy in cutaneous squamous cell carcinoma.
- PMID 41833681PubMed ↗
A multimodal neoadjuvant strategy incorporating PDT, RFA, and ICIs resulted in a notable pathological response and preservation of the sphincter in microsatellite stable low rectal cancer.
- PMID 41831631PubMed ↗
Photobiomodulation pre-treatment enhanced ALA-induced PpIX accumulation and photodynamic therapy response in oral squamous cell carcinoma cells in cell culture.
This information is provided for general education only and is not medical advice. Medical procedures carry individual risks and benefits. Always consult a qualified healthcare professional before making decisions about your treatment.