Radiofrequency ablation

What it is

Radiofrequency ablation (RFA) is a minimally invasive procedure that uses heat generated by high-frequency electrical currents to destroy cancer cells. It is used to treat various types of cancers, including liver, kidney, and thyroid cancers.

What research shows

Studies suggest that RFA is effective in treating small tumors, with high local control rates and low recurrence rates. For example, a study found that RFA achieved a 90% complete response rate in patients with hepatocellular carcinoma. However, more research is needed to determine the optimal patient population and treatment protocols.

Current status

RFA is a viable treatment option for certain types of cancers, particularly small, early-stage tumors. However, its effectiveness in larger tumors and more advanced cancers is less clear, and further research is needed to fully understand its potential.

Key studies

• PMID 41848917

  This study compared the outcomes of no-touch RFA and conventional RFA in treating solitary recurrent hepatocellular carcinoma ≤3 cm and found that no-touch RFA achieved better short- and long-term outcomes.

  PubMed ↗
• PMID 41860416

  This study compared the safety and efficacy of cooled and uncooled microwave ablation systems in treating benign thyroid nodules and found that both systems were safe and effective.

  PubMed ↗
• PMID 41836997

  This case report presented the first documented case of RFA for papillary thyroid microcarcinoma in Indonesia and demonstrated the feasibility of RFA as a treatment option for this condition.

  PubMed ↗