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Stereotactic radiotherapy (SBRT/SRS)

Very high, precisely targeted radiation doses delivered in few sessions.

What it is

Stereotactic radiotherapy (SBRT/SRS) is a precise form of radiation therapy that delivers high doses of radiation to small, well-defined tumors or metastases, often in a single session or a few sessions. This treatment uses radiation to kill cancer cells, and is typically used for cancers that are difficult to treat with surgery or other forms of radiation.

What research shows

Studies suggest that SBRT/SRS can be effective in controlling tumors in various organs, including the brain, lungs, liver, and pancreas. For example, one study found that SBRT/SRS achieved high local control rates in patients with small brain metastases, while another study showed that SBRT/SRS improved survival in patients with oligometastatic prostate cancer. However, more research is needed to fully understand the benefits and limitations of SBRT/SRS.

Current status

SBRT/SRS is a valuable treatment option for patients with small, well-defined tumors or metastases, particularly those who are not candidates for surgery or other forms of radiation. However, its use is still evolving, and more research is needed to determine its optimal role in cancer treatment.

Moderate evidence

Key studies

  • PMID 42559731

    Single-fraction stereotactic radiosurgery (SRS) achieved high local control rates in patients with small brain metastases.

    PubMed ↗
  • PMID 42547024

    SBRT/SRS improved survival in patients with oligometastatic prostate cancer.

    PubMed ↗
  • PMID 42571571

    SBRT/SRS achieved high local control rates in patients with bone-only oligometastatic bladder cancer.

    PubMed ↗

This information is provided for general education only and is not medical advice. Medical procedures carry individual risks and benefits. Always consult a qualified healthcare professional before making decisions about your treatment.