ChemotherapyFDA-approvedFirst-line
Alimta (Pemetrexed)
Generic name: pemetrexed
How it works
Interferes with the growth and spread of cancer cells by blocking the production of DNA and RNA.
Cancer types
Lung Cancer— All patients
Efficacy
In clinical trials, pemetrexed improved overall survival in patients with non-small cell lung cancer, with a median overall survival of approximately 10 months.
Side effects
Severe
This treatment carries a higher risk of serious side effects. Close medical monitoring is required throughout treatment.
Evidence from research
| Study | Cancer type | Stage | Efficacy | |
|---|---|---|---|---|
| Rare Skin Reaction Linked to Lung Cancer Treatment | Lung Cancer | observational | — | Source → |
| New Treatment Combination Tested for Lung Cancer Patients with Brain Metastases | Lung Cancer | phase-1 | — | Source → |
| Testing Sacituzumab Tirumotecan in Advanced Lung Cancer | Lung Cancer | phase-3 | — | Source → |
| Testing Methoxyamine with Cisplatin and Pemetrexed in Advanced Cancer Patients | Lung Cancer | phase-1 | — | Source → |
| Traditional Chinese Medicine May Help Reduce Chemotherapy Side Effects in Lung Cancer Patients | Lung Cancer | phase-3 | The incidence of neurotoxicity was 29.1% in the treatment group, significantly lower than 51.8% in the control group. | Source → |
| Taxane Chemotherapy May Be More Effective Than Pemetrexed in Lung Cancer | Lung Cancer | observational | Taxanes showed numerically longer progression-free survival (PFS; median 8.8 vs 7.9 months) and overall survival (OS; 18.8 vs 15.9 months) versus pemetrexed. | Source → |
| Pemetrexed Side Effects Study Identifies New Safety Signals | Lung Cancer | observational | — | Source → |
| New Treatment Combination Shows Promise for Lung Cancer Patient | Lung Cancer | observational | The treatment successfully prolonged the patient's survival by 3 months. | Source → |
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.