PI3K inhibitorPhase 3 trialInvestigational
Alpelisib
How it works
Blocks the phosphatidylinositol 3-kinase pathway, which is involved in cell growth and survival.
Cancer types
Breast Cancer— PIK3CA-mutated
Efficacy
In clinical trials, alpelisib improved progression-free survival and response rates when combined with hormone therapy in PIK3CA-mutated patients.
Side effects
Moderate
Side effects can be significant and may require dose adjustments or supportive medication, but the treatment is usually continued.
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.