Aromatase inhibitorFDA-approvedAdjuvant
Aromasin
Generic name: exemestane
How it works
Blocks the production of estrogen, which can fuel the growth of hormone receptor-positive breast cancer cells.
Cancer types
Breast Cancer— Hormone receptor-positive
Efficacy
In clinical trials, exemestane improved disease-free survival in patients with hormone receptor-positive breast cancer.
Side effects
Mild
Most people tolerate this treatment well. Side effects are generally manageable and do not require stopping treatment.
Evidence from research
| Study | Cancer type | Stage | Efficacy | |
|---|---|---|---|---|
| Aromatase Inhibitors Linked to Liver Damage in Breast Cancer Patients | Breast Cancer | observational | — | Source → |
| Elacestrant and Exemestane for Advanced Breast Cancer | Breast Cancer | phase-2 | — | Source → |
| Researchers Improve Cancer-Fighting Nanoparticles | Breast Cancer | lab-study | The optimized nanoparticles induced cytotoxicity in MCF-7 cell lines with an IC50 value of 21.46 µg/mL. | Source → |
| Cost-Effectiveness of Breast Cancer Treatment in China | Breast Cancer | phase-3 | — | Source → |
| Alternative Exemestane Dosing for Breast Cancer Prevention | Breast Cancer | phase-2 | Exemestane, 25 mg, given 3 times weekly in compliant patients was noninferior to the once-daily dosage in decreasing serum estradiol. | Source → |
| Everolimus with Exemestane Shows Promise in Advanced Breast Cancer | Breast Cancer | observational | The median progression-free survival was 18.0 months and the overall response rate was 22.7%. | Source → |
| Researchers Identify Key Enzymes in Exemestane Metabolism | Breast Cancer | lab-study | — | Source → |
| Lowering Exemestane Dosage May Improve Tolerability in Breast Cancer Patients | Breast Cancer | phase-2 | — | Source → |
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.