Tyrosine kinase inhibitorFDA-approvedSecond-line
BRAF/MEK inhibitor combination
How it works
Blocks the BRAF V600E mutation and the MEK pathway, two signaling pathways that drive cancer cell growth, allowing the immune system to attack cancer cells.
Cancer types
Melanoma— BRAF V600E-positive
Efficacy
Studies show that around 50% of patients achieved an objective response, with a median progression-free survival of approximately 10.6 months.
Side effects
Moderate
Side effects can be significant and may require dose adjustments or supportive medication, but the treatment is usually continued.
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.