Immunotherapy / PD-1 inhibitorFDA-approvedSecond-line

Durvalumab/tremelimumab

How it works

Durvalumab/tremelimumab is a combination of two immunotherapy drugs: durvalumab and tremelimumab. It works by blocking the PD-1 receptor on immune cells, allowing them to recognize and attack cancer cells, and also by increasing the production of cytokines, which are signaling molecules that help to activate the immune system.

Cancer types

Pancreatic CancerAll patients

Efficacy

In clinical trials, durvalumab/tremelimumab improved overall survival in patients with pancreatic cancer, with approximately 26% of patients achieving a partial response.

Side effects

Mild

Most people tolerate this treatment well. Side effects are generally manageable and do not require stopping treatment.

Evidence from research

StudyCancer typeStageEfficacy
Testing Radiotherapy and Immunotherapy for Small Cell Lung CancerLung Cancerphase-1Source →

This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.