Tyrosine kinase inhibitorFDA-approvedFirst-line
Gilotrif
Generic name: afatinib
How it works
Blocks the epidermal growth factor receptor (EGFR) tyrosine kinase, which is involved in the growth and spread of cancer cells.
Cancer types
Lung Cancer— EGFR-mutated
Efficacy
In clinical trials, afatinib improved response rates and progression-free survival in patients with EGFR-mutated non-small cell lung cancer.
Side effects
Moderate
Side effects can be significant and may require dose adjustments or supportive medication, but the treatment is usually continued.
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.