ChemotherapyInvestigationalSecond-line

MM-398

Generic name: nolotinib

How it works

MM-398 is a topoisomerase inhibitor that prevents cancer cells from growing and dividing.

Cancer types

Pancreatic Cancer— All patients

Efficacy

MM-398 in combination with gemcitabine has been shown to improve overall survival in patients with metastatic pancreatic cancer, compared to gemcitabine alone, in clinical trials.

Side effects

Moderate

Side effects can be significant and may require dose adjustments or supportive medication, but the treatment is usually continued.

This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.