ChemotherapyPhase 3 trialInvestigational

MM-398

Generic name: naptumomab estafenatox

How it works

MM-398 is a formulation of irinotecan that is designed to be more easily absorbed by cancer cells, causing cell death.

Cancer types

Pancreatic CancerAll patients

Efficacy

In clinical trials, MM-398 in combination with 5-fluorouracil and leucovorin improved median overall survival to approximately 6.1 months compared to 5-fluorouracil and leucovorin alone.

Side effects

Severe

This treatment carries a higher risk of serious side effects. Close medical monitoring is required throughout treatment.

This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.