ChemotherapyFDA-approvedFirst-line

Pemetrexed

How it works

Interferes with the growth and spread of cancer cells by blocking the production of DNA and RNA.

Cancer types

Lung CancerAll patients

Side effects

Severe

This treatment carries a higher risk of serious side effects. Close medical monitoring is required throughout treatment.

Evidence from research

StudyCancer typeStageEfficacy
New Treatment Combination Tested for Lung Cancer Patients with Brain MetastasesLung Cancerphase-1Source →
Testing Sacituzumab Tirumotecan in Advanced Lung CancerLung Cancerphase-3Source →
Testing Methoxyamine with Cisplatin and Pemetrexed in Advanced Cancer PatientsLung Cancerphase-1Source →
Combining Medications Improves Lung Cancer Treatment for Some PatientsLung Cancerphase-3Combination therapy significantly prolonged median progression-free survival compared with monotherapy (19.78 vs 16.53 months; hazard ratio, 0.58; 95% confidence interval, 0.34-0.97).Source →
New Treatment for Lung CancerLung CancerobservationalSource →

This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.