Tyrosine kinase inhibitorFDA-approvedSecond-line
Zykadia
Generic name: ceritinib
How it works
Blocks the anaplastic lymphoma kinase (ALK) tyrosine kinase, which is involved in the growth and spread of cancer cells.
Cancer types
Lung Cancer— ALK-positive
Efficacy
In clinical trials, ceritinib improved response rates and progression-free survival in patients with ALK-positive non-small cell lung cancer.
Side effects
Moderate
Side effects can be significant and may require dose adjustments or supportive medication, but the treatment is usually continued.
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.