Hormone therapyFDA-approvedFirst-line
Apalutamide
How it works
Blocks the action of testosterone on prostate cancer cells, preventing them from growing.
Cancer types
Prostate Cancer— All patients
Efficacy
Apalutamide has been shown to significantly improve metastasis-free survival in patients with non-metastatic castration-resistant prostate cancer.
Side effects
Mild
Most people tolerate this treatment well. Side effects are generally manageable and do not require stopping treatment.
Evidence from research
| Study | Cancer type | Stage | Efficacy | |
|---|---|---|---|---|
| Study of Prostate Cancer Treatment with Apalutamide or Enzalutamide | Prostate Cancer | phase-3 | — | Source → |
| Testing Apalutamide Alone for Metastatic Prostate Cancer | Prostate Cancer | phase-3 | — | Source → |
| Testing Low Dose Apalutamide for Prostate Cancer | Prostate Cancer | phase-2 | — | Source → |
| Rare Skin Reaction Found in Prostate Cancer Patient Taking Apalutamide | Prostate Cancer | observational | — | Source → |
| Comparing Two Treatments for Advanced Prostate Cancer | Prostate Cancer | observational | The apalutamide group showed significantly higher CRPC-free probability at 24 months (68.2% vs. 39.8%, p < 0.001) compared to the bicalutamide group. | Source → |
| Prostate Cancer Cells May Resist Apalutamide Treatment | Prostate Cancer | lab-study | — | Source → |
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.