Hormone therapyFDA-approvedFirst-line
Bicalutamide
How it works
Blocks the action of testosterone on prostate cancer cells, preventing them from growing.
Cancer types
Prostate Cancer— All patients
Efficacy
In clinical trials, bicalutamide significantly improved time to progression and overall survival compared to placebo.
Side effects
Mild
Most people tolerate this treatment well. Side effects are generally manageable and do not require stopping treatment.
Evidence from research
| Study | Cancer type | Stage | Efficacy | |
|---|---|---|---|---|
| Prostate Cancer Treatment Study | Prostate Cancer | phase-2 | — | Source → |
| Comparing Two Treatments for Advanced Prostate Cancer | Prostate Cancer | observational | The apalutamide group showed significantly higher CRPC-free probability at 24 months (68.2% vs. 39.8%, p < 0.001) compared to the bicalutamide group. | Source → |
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.