ChemotherapyFDA-approvedSecond-line

Docetaxel

How it works

Interferes with cell division, preventing cancer cells from growing and dividing.

Cancer types

Breast CancerAll patients
Prostate CancerAll patients
Lung CancerAll patients

Efficacy

Docetaxel has been shown to improve overall survival and delay disease progression in patients with advanced prostate cancer.

Side effects

Severe

This treatment carries a higher risk of serious side effects. Close medical monitoring is required throughout treatment.

Evidence from research

StudyCancer typeStageEfficacy
Comparing Treatments for Advanced Prostate CancerProstate Cancerphase-2Source →
Testing Combination Therapy for Advanced Prostate CancerProstate Cancerphase-3Source →
Abiraterone and Antiandrogen Therapy for Metastatic Prostate CancerProstate Cancerphase-2Source →
New Treatment Combination Shows Promise for HER2 Positive Breast CancerBreast Cancerphase-3Overall survival was longer in the pyrotinib group (hazard ratio 0.64 (95% confidence interval (CI) 0.46 to 0.89); nominal one-sided P=0.004).Source →
Evaluating Nivolumab and Docetaxel for Advanced Lung CancerLung CancerpreclinicalSource →
Study of a New Medicine for Lung CancerLung Cancerphase-3Source →
New Insights into Prostate Cancer Treatment OptionsProstate Cancermeta-analysisDarolutamide + docetaxel + ADT showed significant benefit over docetaxel + ADT, ADT and standard-nonsteroidal-antiandrogen + ADT in all analyses.Source →
Eugenol Derivatives Enhance Chemotherapy Effectiveness in Prostate Cancer CellsProstate Cancerlab-studySource →
Chemotherapy Combination Affects Lung Cancer Cells in Lab ExperimentsLung Cancerlab-studySource →
Hospitalization Risks Vary for Prostate Cancer Patients on Different TreatmentsProstate CancerobservationalSource →
Early Docetaxel and Enzalutamide for Prostate Cancer: New InsightsProstate Cancerphase-3Among those assigned no enzalutamide, OS was longer with the planned use of early docetaxel (HR 0.90, 95% CI 0.82-0.98), especially in high-volume disease.Source →
METTL14's Role in Lung Cancer Progression and Docetaxel ResistanceLung Cancerlab-studySource →
Atezolizumab Compared to Docetaxel in Lung Cancer TreatmentLung Cancermeta-analysisAtezolizumab had better efficacy than docetaxel for overall survival (HR: 0.77, 95% CI: 0.73 to 0.81).Source →
New Nanoparticle Delivery System Shows Promise for Breast Cancer TreatmentBreast Cancerlab-studyThe cRGD-HA-CDU@DTX system exhibited a 64.12% tumor growth reduction.Source →
Real-world safety of docetaxel for lung cancer treatmentLung CancerobservationalSource →
GRIM-19's Role in Prostate Cancer TreatmentProstate Cancerlab-studySource →

This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.