Hormone therapyFDA-approvedSecond-line
Erleada
Generic name: apalutamide
How it works
Blocks the action of testosterone on cancer cells, slowing growth.
Cancer types
Prostate Cancer— All patients
Efficacy
Studies show that apalutamide can slow cancer growth and reduce symptoms in around 80% of patients.
Side effects
Moderate
Side effects can be significant and may require dose adjustments or supportive medication, but the treatment is usually continued.
Evidence from research
| Study | Cancer type | Stage | Efficacy | |
|---|---|---|---|---|
| Study of Prostate Cancer Treatment with Apalutamide or Enzalutamide | Prostate Cancer | phase-3 | — | Source → |
| Testing Apalutamide Alone for Metastatic Prostate Cancer | Prostate Cancer | phase-3 | — | Source → |
| Testing Low Dose Apalutamide for Prostate Cancer | Prostate Cancer | phase-2 | — | Source → |
| Rare Skin Reaction Found in Prostate Cancer Patient Taking Apalutamide | Prostate Cancer | observational | — | Source → |
| Comparing Two Treatments for Advanced Prostate Cancer | Prostate Cancer | observational | The apalutamide group showed significantly higher CRPC-free probability at 24 months (68.2% vs. 39.8%, p < 0.001) compared to the bicalutamide group. | Source → |
| Prostate Cancer Cells May Resist Apalutamide Treatment | Prostate Cancer | lab-study | — | Source → |
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.