Hormone therapyFDA-approvedFirst-line
Relugolix
How it works
Blocks the production of androgens (male hormones) that fuel prostate cancer growth, slowing tumor growth.
Cancer types
Prostate Cancer— All patients
Efficacy
Studies show that relugolix can improve metastasis-free survival in patients with non-metastatic castration-resistant prostate cancer.
Side effects
Mild
Most people tolerate this treatment well. Side effects are generally manageable and do not require stopping treatment.
Evidence from research
| Study | Cancer type | Stage | Efficacy | |
|---|---|---|---|---|
| Testing Relugolix with Radiation Therapy for Advanced Prostate Cancer | Prostate Cancer | phase-2 | — | Source → |
| Prostate Cancer Study: Relugolix and SBRT Treatment | Prostate Cancer | phase-2 | — | Source → |
| Study of Relugolix in Patients with Prostate Cancer | Prostate Cancer | preclinical | — | Source → |
| New Oral Treatment for Advanced Prostate Cancer Shows Promise | Prostate Cancer | phase-3 | Relugolix was associated with a 54% reduction in the risk of major adverse cardiovascular events. | Source → |
| Potential New Side Effects of Cancer Treatment Relugolix | Prostate Cancer | observational | — | Source → |
| New Study Compares Cancer Treatment Efficacy in Men with Heart Conditions | Prostate Cancer | phase-3 | A 54% lower incidence of major adverse cardiac events was reported in men treated with relugolix vs leuprolide. | Source → |
| Concerns Raised Over Relugolix Approval for Prostate Cancer | Prostate Cancer | phase-3 | — | Source → |
| Relugolix vs Leuprolide for Advanced Prostate Cancer | Prostate Cancer | phase-3 | 97% of men taking relugolix achieved sustained castration through 48 weeks, compared to 89% of men receiving leuprolide. | Source → |
| Advances in Treating Advanced Prostate Cancer | Prostate Cancer | review | — | Source → |
| Managing Metastatic Prostate Cancer: New Treatment Options | Prostate Cancer | review | — | Source → |
This information is provided for general education only and is not medical advice. Always consult a qualified healthcare professional before making treatment decisions.